cancer epidemiology, biomarkers & prevention

Jain V, Bhardwaj A: Pneumonia, Pathology In: The definition and classification of pneumonia. Guide for authors - Cancer Epidemiology - ISSN 1877-7821 Bao W, Xu GF, Lu JC, Snetselaar LG, Wallace RB. You may choose to submit your manuscript as a single Word or PDF file to be used in the refereeing process. In 2016, the prevalence of current cigarette smoking among adults was 15.5%, which was substantially declined from 20.9% in 2005 [147]. Additional factors may include smoking, diet, physical activity, specific medications, and occupational factors. Secondhand smoke, or side-stream smoke, is an indirect carcinogenic exposure resulting from the burning of tobacco products. Material published in Cancer Epidemiology, Biomarkers & Prevention is covered and protected by copyright. Key substance use and mental health indicators in the United States: Results from the 2016 National Survey on Drug Use and Health (HHS Publication No. Figure 2b shows age-adjusted lung cancer incidence rates for females in the United States, 2011 2015, using data from U.S. Cancer Statistics Working Group. Guide for Authors. Zhu SH, Sun JY, Bonnevie E, Cummins SE, Gamst A, Yin L, et al. Individuals who are infected with HIV are at increased for many cancers, attributed to many factors including HIV-related immunosuppression which impairs control of oncogenic viral infections, mediators of inflammation, and co-infection with oncogenic viruses such as Hepatitis B and C [122-124]. Unauthorized use of these marks is strictly prohibited. URL at: Tsai J, Homa DM, Gentzke AS, Mahoney M, Sharapova SR, Sosnoff CS, et al. The https:// ensures that you are connecting to the Accessibility Further, research is needed on the feasibility and efficacy of providing smoking cessation treatment in the lung cancer screening setting. Exposure to Secondhand Smoke Among Nonsmokers - United States, 1988-2014, Office of the Surgeon General. For detailed metrics about Cancer Epidemiology, Biomarkers & Prevention and the other AACR journals see AACR Journals Metrics. Minnix JA, Karam-Hage M, Blalock JA, Cinciripini PM. Both the USPSTF and CMS guidelines recommend smoking cessation interventions for individuals who enter a lung cancer screening program. The findings reinforce the importance of implementing and strengthening resource-stratified and targeted cancer prevention and control programs in all parts of the world to further reduce or halt the rising cancer burden. Association of Cigarette, Cigar, and Pipe Use With Mortality Risk in the US Population, Systematic review with meta-analysis of the epidemiological evidence in the 1900s relating smoking to lung cancer. McCarthy WJ, Meza R, Jeon J, Moolgavkar SH. To address potential sex-specific differences in lung cancer risk, OKeeffe et al [15] conducted a systematic review and meta-analysis of prospective cohort studies on the sex-specific association of smoking with the risk of fatal and non-fatal lung cancer. Epub 2009 Apr 29. C. pneumoniae infection was significantly associated with a 1.2-fold increased risk of lung cancer in prospective studies and 2.2-fold increased risk in retrospective studies. In 2004, the Genetic Epidemiology of Lung Cancer Consortium revealed the first evidence for a major susceptibility locus influencing lung cancer risk to a region on 6q2325 [138]. Though primary prevention (smoking prevention and cessation) mitigates risk and mortality, former smokers remain at significant risk of dying from lung cancer (Figure 10) [148]. A separate meta-analysis that assessed the association between secondhand smoke and lung cancer in Japanese non-smokers found a 28% increased risk [54]. Program Director, Risk Factor Assessment Branch The publisher's final edited version of this article is available at, Lung cancer, epidemiology, statistics, disparities, risk factors, prevention early detection, lung cancer screening, epidemiology of lung cancer. Cancer Prevention & Early Detection Facts & Figures, Cancer Treatment & Survivorship Facts & Figures, Cancer Facts & Figures for African American/Black People, Cancer Facts & Figures for Hispanic and Latino People, Updated Review of Major Cancer Risk Factors and Screening Test Use in the United States, with a Focus on Changes During the COVID-19 Pandemic,, Cancer Prevention & Early Detection Facts & Figures 2023-2024 (PDF), SLIDE SET: Cancer Prevention & Early Detection 2023-2024 (PPT), Press release: New ACS Report Finds Smoking, Alcohol Use, Physical Inactivity Decreased During COVID-19; Worsening Trends in Obesity, Cervical Cancer Screening, Referrals to patient-related programs or resources, Donations, website, or event-related assistance. sharing sensitive information, make sure youre on a federal Furthermore, the timing of a pneumonia diagnosis can coincide with or confound the diagnosis of lung cancer and pneumonia may be a complication of lung cancer such as post-obstructive pneumonia [115]. In the United States, smoked cannabis is estimated to be the most commonly inhaled drug after tobacco with an estimated 7,000 new users a day [78]. Clipboard, Search History, and several other advanced features are temporarily unavailable. Estimated age-standardized rates (ASR) for lung cancer mortality worldwide. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Because biomarkers are sometimes related to risk of disease, they are important in cancer control research. An official website of the United States government. Medical Care Costs Associated with Cancer Survivorship in the United The identification of biomarkers of pancreatic cancer survival are urgently needed given the high fatality of this disease. Would you like email updates of new search results? Federal government websites often end in .gov or .mil. Clipboard, Search History, and several other advanced features are temporarily unavailable. A pooled analysis from [83] the International Lung Cancer Consortium of 2,159 lung cancer cases and 2,985 controls found little evidence for an increased risk of lung cancer among habitual or longterm cannabis smokers. Hori M, Tanaka H, Wakai K, Sasazuki S, Katanoda K. Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies. However, it should be noted that studies to date have been limited by sample size, self-report, and confounding (e.g., many marijuana users also report tobacco use). As such, research in potential lung cancer disparities has not disentangled sex vs. gender. Geographically, lung cancer mortality follows a pattern similar to incidence including the highest rates observed in the South (Figures 4a and and4b4b). : The Health of Lesbian, Gay, Bisexual, and Transgender People: Building a Foundation for Better Understanding. A pooled analysis from the International Lung Cancer Consortium and a meta-analysis reported that previous history of tuberculosis was associated with a 48% and 76% increased risk of lung cancer, respectively [105, 107]. Accessibility Read More About the Journal Editors Elizabeth A. Platz We connect patients, caregivers, and family members with valuable services and resources. Asthma is a common childhood disease affecting approximately 300 million people worldwide [108]. Unequivocally, tobacco smoking is the most important and prevalent lung cancer risk factor. Select theLiveChat button at the bottom of the page. vermam@mail.nih.gov, Dana Wolff-Hughes, PhD Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung. Current Cigarette Smoking Among Adults - United States, 2016, Patterns of absolute risk of lung cancer mortality in former smokers, Risk models to select high risk candidates for lung cancer screening. PCa remains the second most common cancer among men worldwide. Epub 2011 Jan 12. 2014 Jun;65(6):1046-55. doi: 10.1016/j.eururo.2013.12.062. Published meta-analyses have reported a 2 to 3-fold risk of lung associated with a history of COPD, emphysema, or chronic bronchitis [104-106]. Epub 2021 Oct 26. Tobacco smoking is the major risk factor for COPD [103] so it is unexpected to find a positive association between COPD and lung cancer. Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear. Cancer Epidemiology, Biomarkers & Prevention (CEBP) (Print ISSN: 1055-9965: Online ISSN 1538-7755) is published monthly, one volume/year, by the American Association for Cancer Research, Inc. (AACR). Evaluation of the lung cancer risks at which to screen ever- and never-smokers: screening rules applied to the PLCO and NLST cohorts. Wang H, Yang L, Zou L, Huang D, Guo Y, Pan M, et al. Wu QJ, Xie L, Zheng W, Vogtmann E, Li HL, Yang G, et al. While risk of lung cancer and death is lower for individuals using these products compared to those who smoke cigarettes, it should be noted that these are not safer alternatives to cigarette smoking as the lower point estimates are likely attributed to lower smoking intensity and perhaps lesser degrees of inhalation of these products. A meta-analysis [118] of 12 studies including 2,595 lung cancer cases and 2,585 controls reported that C. pneumoniae infection was associated with a 1.5-fold increased risk of lung cancer. Federal government websites often end in .gov or .mil. Projections of the cost of cancer care in the United States: 2010-2020. Cancer Epidemiology Biomarkers & Prevention 8600 Rockville Pike U.S. Cancer Statistics Data Visualizations Tool, based on November 2017 submission data (1999-2015): U.S. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute (www.cdc.gov/cancer/dataviz), June 2018. A systematic search was performed in July 2022 using PubMed/MEDLINE and EMBASE biomedical databases. Engels EA, Brock MV, Chen J, Hooker CM, Gillison M, Moore RD. Office of the Surgeon General: The health consequences of smoking--50 years of progress : a report of the surgeon general. J Natl Cancer Inst. Tammemagi MC, Church TR, Hocking WG, Silvestri GA, Kvale PA, Riley TL, et al. After excluding nearly 49,000 individuals who reported multiple tobacco product use, risk of lung cancer death among daily users was highest among cigarette users (12.7-fold increased risk), followed by daily cigar use (4.2-fold increased risk), and then daily pipe users (1.7-fold increased risk). The biennial American Cancer Society report Cancer Prevention and Early Detection Facts & Figures, 2023-2024 reviews and provides the latest data on major modifiable cancer risk factors, preventative vaccinations, and use of cancer screening tests. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Lung cancer and socioeconomic status in a pooled analysis of case-control studies. Avoidable risk factors for PCa may include factors such as smoking, diet, physical activity, specific medications, and certain occupations. Program in Genetic Epidemiology and Statistical Genetics Cancer epidemiology, biomarkers & prevention, and cancer prevention research: two journals, a common goal Cancer Epidemiol Biomarkers Prev. Subgroup analyses also demonstrated significant increases for non-Hispanic Whites, Asians, males, and females. doi: 10.5694/mja2.50881. Branch Chief, Methods and Technologies Branch In 2019 an estimated 228,150 new cases of lung cancer are expected. For descriptions and length requirements of the article types available to submitting authors, see the journals Categories of Articles. Prolonged lung cancer screening reduced 10-year mortality in the MILD trial: new confirmation of lung cancer screening efficacy. Novel smoking cessation strategies tailored to the lung cancer screening setting will likely amplify the survivorship gains expected from screening alone [154]. Duan P, Hu C, Quan C, Yi X, Zhou W, Yuan M, et al. Overall national costs in 2015 were $183 billion and projected to increase 34% to $246 billion by 2030, based only on population growth. Croft JB, Wheaton AG, Liu Y, Xu F, Lu H, Matthews KA, et al. Among 41 studies, 24 reported on platinum-based chemotherapy, eight on non-platinum-based chemotherapy, six on immunotherapy, two on targeted therapy, and one on surgery. Phone: (215) 440-9300; or Toll Free: (855) 744-4667 615 Chestnut Street | 17th Floor | Philadelphia, PA 19106-4404 Digital biomarkers are physiological and behavioral measures derived from digital technology that explain or predict health outcomes. The Health Consequences of Smoking50 Years of Progress: A Report of the Surgeon General, 2014. NCI is currently participating in the following notices of funding opportunities that are relevant to biomarkers research: EGRP joins with other NCI Divisions, Offices, and Centers and other Institutes and Centers at the National Institutes of Health (NIH) to fund grant applications submitted in response to notices of funding opportunities. Hoggart C, Brennan P, Tjonneland A, Vogel U, Overvad K, Ostergaard JN, et al. Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, et al. Although only around 15% of smokers develop lung cancer, 80 to 90% of lung cancer diagnoses are attributed to tobacco smoking in the United States [3]. Philadelphia, PA 19106-4404 Cancer Epidemiology publishes original research, prioritizing studies that contribute new information about cancer causes, prevention and control. This site needs JavaScript to work properly. Copyright 2023. In addition, over the last decade, fewer adolescents perceive moderate or regular use of marijuana as a health risk [85, 86]. 1998 Mar;6(2):97-106. doi: 10.1002/j.1550-8528.1998.tb00322.x. Although cigarettes remain the most prevalent form of tobacco use in the United States, other tobacco products including pipes, cigars, and water pipes (e.g., hookah) are still common and have been associated with increased risk and mortality of lung cancer. Yang Y, Dong J, Sun K, Zhao L, Zhao F, Wang L, et al. Dietary Fat Intake and Lung Cancer Risk: A Pooled Analysis, A Healthy Dietary Pattern Reduces Lung Cancer Risk: A Systematic Review and Meta-Analysis. The https:// ensures that you are connecting to the Before Among men, the incidence rate of lung adenocarcinoma has been on the rise since the 1970s and the incidence rate for lung adenocarcinoma surpassed squamous cell carcinoma around 1994 (Figure 8b). Patient summary: Prostate cancer (PCa) remains the second most common cancer among men, and screening for PCa is likely to increase in the future. Prostate cancer (PCa) remains the second most common cancer among men, and screening for PCa is likely to increase in the future. Worldwide, lung cancer is the leading cause of cancer death in men and the second-leading cause in women. Tuberculosis is a communicable infectious disease transmitted by cough aerosol and is caused by the Mycobacterium tuberculosis bacterium. J Natl Cancer Inst. Current estimates of the economic cost of obesity in the United States. Copyright 2023 by the American Association for Cancer Research. Thun MJ, Carter BD, Feskanich D, Freedman ND, Prentice R, Lopez AD, et al. High outofpocket spending and financial hardship at the end of life among cancer survivors and their families. HIV infection, aging, and immune function: implications for cancer risk and prevention, The pattern of non-AIDS-defining cancers in the HIV population: epidemiology, risk factors and prognosis. Conquering cancer disparities: new opportunities for cancer epidemiology, biomarker, and prevention research. Cancer Epidemiology, Biomarkers & Prevention is abstracted and/or indexed in in BIOSIS Previews, Current Contents/Clinical Medicine, MEDLINE, Science Citation Index, Scopus, and Web of Science. National Library of Medicine Copyright 2023 The President and Fellows of Harvard College, Harvard T.H. 2022 Feb 1;2(2022):CD014217. In 2019, an estimated 142,670 deaths are expected to occur, or about 23.5% of all cancer deaths. Incidence and risk of lung cancer in HIV-infected patients, Early landmark studies of smoking and lung cancer. Data source: GLOBOCAN 2018. 2016 Jan;25(1):16-27. doi: 10.1158/1055-9965.EPI-15 . The five-year relative survival rate for all lung cancers (non-small cell lung cancer [NSCLC] and small cell lung cancer combined) is 19% and the five-year survival is higher for non-small cell lung cancer (23%) than small cell lung cancer (6%) [3, 4]. Z99 CA999999/ImNIH/Intramural NIH HHS/United States. Additionally, the impact of marijuana and electronic-cigarettes on lung cancer risk needs to be clarified. Yabroff KR, Lamont EB, Mariotto A, Warren JL, Topor M, Meekins A, Brown ML. Besides welcoming manuscripts that address individual subjects in any of the relevant disciplines, CEBP editors encourage the submission of manuscripts with a transdisciplinary approach. https://seer.cancer.gov/statfacts/html/lungb.html, http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html, https://epi.grants.cancer.gov/cancer_risk_prediction/lung.html, http://lungcancerrisk.s3-website-us-east-1.amazonaws.com/, http://www.ncsl.org/bookstore/state-legislatures-magazine/marijuana-deep-dive.aspx, https://monographs.iarc.fr/agents-classified-by-the-iarc/, https://dceg.cancer.gov/research/cancer-types/lung/sherlock-lung-study, https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/lung-cancer-screening, https://www.cms.gov/medicare-coverage-database/details/nca-decision-memo.aspx?NCAId=274, 25% to 28% increased risk vs. never smoker, Other tobacco use (cigars, pipes, water pipes), History of COPD, emphysema, or chronic bronchitis. A meta-analysis [74] of 287 epidemiological studies of lung cancer found that pipe use only was associated with a 3.3-fold increased risk of lung cancer and cigar use only was associated with a 2.95-fold increased risk. Although tuberculosis primarily affects the lungs, it can affect other parts of the body. Careers. Percent of lung cancer cases at diagnosis and 5-year relative survival by stage. Most commonly, pneumococcal disease is an infection caused by the Streptococcus pneumoniae bacterium which can infect the lungs (pneumonia), bloodstream (bacteremia), and tissues and fluids surrounding the brain and spinal cord (meningitis). Several studies have investigated abnormally expressed miRNAs as biomarkers in breast cancer tissue . Hiscock R, Bauld L, Amos A, Fidler JA, Munafo M. Socioeconomic status and smoking: a review. Cancer Progress and Priorities: Lung Cancer - PMC 2020 Dec;213 Suppl 11:S3-S32.e1. Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Wiest JS, et al. Lung cancer mortality reduction by LDCT screening-Results from the randomized German LUSI trial. Accessibility The mortality rate among men is 51.6 per 100,000 and 34.4 per 100,000 for women. Data from 99 cohort studies representing more than 7 million individuals and over 50000 incident cases of lung cancer found no evidence for sex-specific differences for risk of smoking-related lung cancer. Keywords: and transmitted securely. Breast Cancer Epidemiology. Flavored Tobacco Product Use in Youth and Adults: Findings From the First Wave of the PATH Study (2013-2014). The .gov means its official. LLPi: Liverpool Lung Project Risk Prediction Model for Lung Cancer Incidence. To defray publication costs and to support other AACR programs, publication in Cancer Epidemiology, Biomarkers & Prevention involves the payment of a fixed publication fee and an additional fee for any color figures. Danielle Carrick, PhD, MHS An official website of the United States government. The authors declare no potential conflicts of interest. Figure 6 shows the percentage of lung cancer cases diagnosed in the U.S. by stage and their respective 5-year survival rates using data from SEER 18 (https://seer.cancer.gov/statfacts/html/lungb.html). eCollection 2023. Residential radon and lung cancer risk: an updated meta- analysis of case-control studies, Lung cancer: epidemiology, etiology, and prevention. Olsson AC, Vermeulen R, Schuz J, Kromhout H, Pesch B, Peters S, et al. Worldwide, 3% to 14% of lung cancers are attributed to radon exposure and the variance is attributed to geographic differences in radon concentration and on the method of calculation [87]. Prevalence and Distribution of E-Cigarette Use Among US Adults: Behavioral Risk Factor Surveillance System, 2016. Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide, Electronic cigarettes. government site. Lung cancer survival has only marginally improved over the last several decades, but the availability of screening and early detection by low-dose computer tomography and advances in targeted treatments and immunotherapy will likely decrease mortality rates and improve patient survival outcomes in the near future. The site is secure. 2023 May 8;13:1127086. doi: 10.3389/fonc.2023.1127086. We combined phase-specific attributable costs with prevalence projections to estimate national costs from 2015 through 2030. 615 Chestnut Street, 17th Floor National Library of Medicine Email: pubsales@aacr.org, Cancer Epidemiology, Biomarkers & Prevention Editorial Office Cancer Epidemiology, Biomarkers & Prevention publishes original, peer-reviewed research on cancer causation, mechanisms of carcinogenesis, prevention, and survivorship. Smoking and health: report of the Advisory Committee to the Surgeon General of the Public Health Service. eCollection 2023. Fader AN, Arriba LN, Frasure HE, von Gruenigen VE. Black lung cancer patients (16%) have overall lower 5year relative survival rate than Whites (19%) which is consistent for localized (52% vs. 56%) and regional disease (27% vs 30%), but not for distant disease (5% vs. 5%). Editorial oversight of Cancer Epidemiology, Biomarkers & Prevention and decisions on manuscripts submitted to the journal are the responsibility of the Editorial Board with support from journal staff. Lerner CA, Sundar IK, Yao H, Gerloff J, Ossip DJ, McIntosh S, et al. Rates were age-standardized to the 1966 . Additionally, e-cigarette use among US youths is associated with increased risk of initiation of traditional cigarette use [63, 64]. {currentyear} American Cancer Society, Inc. All rights reserved. Unable to load your collection due to an error, Unable to load your delegates due to an error. These instructions contain important guidelines on authorship, publishing ethics, availability of materials and data, and data analysis and reporting. Four hundred and sixty brands of e-cigarettes and counting: implications for product regulation. Diabetes Care. To be useful in cancer epidemiology, applications of biomarkers should reduce misclassification of exposures and disease, enhance detection of exposure-disease associations, or increase opportunities for intervention. de Groot PM, Wu CC, Carter BW, Munden RF. Submit your article to Cancer Epidemiology, Biomarkers & Prevention. This conclusion extends to all secondhand smoke exposure, regardless of location. A meta-analysis published in 2018 of twelve studies found that secondhand smoke exposure compared to never smokers without such exposure was associated with a 25% increased risk of lung cancer [53]. Established and putative risk lung cancer risk factors.
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